MOTS-C

All products are used for research use only

MOTS-c peptide (short for "Mitochondrial Open Reading Frame of the 12S rRNA Type-c") is a small protein naturally produced in the mitochondria of cells. It plays a key role in regulating metabolism and cellular health.

What is MOTS-c used for?

MOTS-c is being studied and used (often in peptide therapy or research settings) for its potential in:

• Enhancing metabolic health

• Promoting fat loss

• Increasing physical performance and endurance

• Improving insulin sensitivity

• Fighting age-related decline

Benefits of MOTS-c peptide:

1. Supports Weight Loss & Fat Metabolism
   MOTS-c helps the body use fat more efficiently for energy, which may aid in weight loss and fat burning—especially in the abdomen.

2. Improves Insulin Sensitivity
   It can help regulate blood sugar and may be beneficial for people with insulin resistance or prediabetes.

3. Boosts Cellular Energy & Endurance
   By improving mitochondrial function, MOTS-c can increase stamina and physical performance.

4. Anti-Aging Effects
   Some research suggests it helps delay age-related physical and metabolic decline, supporting muscle mass and cognitive function in aging individuals.

5. May Reduce Inflammation
   It has been associated with reduced markers of inflammation, which benefits overall health.

6. Enhances Muscle Recovery
   Athletes sometimes use it to support faster recovery and improve muscle efficiency.

How is it used?

MOTS-c is typically administered via subcutaneous injection, though it's still considered experimental and not approved by the FDA for mainstream medical use. It’s often used in anti-aging clinics or under the guidance of specialists in regenerative medicine.

Scientific Studies on MOTS-c

1. Metabolic Function & Obesity

   • Study: Published in Cell Metabolism (2015), researchers found that MOTS-c helps regulate metabolic homeostasis.

   • Findings: It improved insulin sensitivity and reduced weight gain in mice fed a high-fat diet. It mimicked exercise-like effects on metabolism.

2. Exercise & Endurance

   • Study: Research in Nature Communications (2020) showed MOTS-c enhances physical performance.

   • Findings: Mice given MOTS-c ran longer and farther. It also improved skeletal muscle health and mitochondrial function.

3. Aging and Longevity

   • Study: Older mice treated with MOTS-c had improved physical capacity and muscle strength.

   • Findings: Suggests MOTS-c can counteract age-related decline. The same study showed increased expression of genes related to stress resistance.

4. Diabetes and Insulin Resistance

   • Findings: MOTS-c improves insulin sensitivity and glucose uptake in cells. This suggests potential use for people with Type 2 diabetes or metabolic syndrome.

5. Human Trials

   • As of now, human clinical trials are limited, but preliminary data suggest MOTS-c levels are lower in people with obesity and metabolic disorders—supporting its therapeutic potential.

Safety Profile

• Currently considered safe in animal studies at normal research doses.

• Side effects are rare but may include:

  • Redness or irritation at the injection site

  • Fatigue (initially in some users)

  • Temporary lightheadedness (due to blood sugar regulation)

⚠️ Important Notes:

• Not FDA-approved: MOTS-c is still considered experimental and is not approved as a drug or treatment.

• Should only be used under medical supervision, especially if you have underlying health conditions.

• Quality matters: If using peptide therapy, the source should be reputable and pharmaceutical-grade to ensure safety and effectiveness.